According to The Telegraph, Spurs owner Joe Lewis has informed chairman Daniel Levy to either sell Kane or renew his contract that expires next summer.
The England international is not expected to renew his contract with the London outfit and prefers to move elsewhere.
Kane was Erik ten Hag’s ideal striker target, but the Red Devils turned their attention to other centre-forwards to avoid a summer-long transfer saga with Levy.
Atalanta striker Rasmus Hojlund is touted with a switch to Old Trafford, with United expected to make an official bid this week.
Signing Harry Kane could send Man Utd to Dreamland
The Red Devils have already spent £107m to sign Mason Mount and Andre Onana this summer.
They will need another £100m to bring Kane to the Theatre of Dreams.
It won’t be easy for United as they are working with a limited transfer budget and have to operate within the Financial Fair Play rules.
If Levy is ready to sell Kane, Ten Hag could demand United to turn their attention back to the Englishman.
The 30-year-old is one of the best strikers in the Premier League era. His arrival could transform United into a robust title challenger.
Levy can still make matters difficult for the Red Devils. He would prefer to offload his best player to a foreign club rather than to a direct PL rival.
Bayern Munich have earmarked Kane as their top target and are preparing a third offer for the forward.
The Bundesliga giants are yet to replace Robert Lewandowski, who left last summer for Barcelona.
A move to the Bavarians will take Kane close to winning trophies. However, that will hamper his ambition to break Alan Shearer’s Premier League goals record.